BDBM50227672 2-(2-(1-ethyl-3-methyl-3-(4-(trifluoromethoxy)phenyl)ureido)-2,3-dihydro-1H-inden-5-ylthio)-2-methylpropanoic acid::CHEMBL250037

SMILES: CCN(C1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)N(C)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=ONJFGRBKPNRQCO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Rattus norvegicus)	BDBM50227672 (2-(2-(1-ethyl-3-methyl-3-(4-(trifluoromethoxy)phen...) Show SMILES CCN(C1Cc2ccc(SC(C)(C)C(O)=O)cc2C1)C(=O)N(C)c1ccc(OC(F)(F)F)cc1 |w:3.2| Show InChI InChI=1S/C24H27F3N2O4S/c1-5-29(22(32)28(4)17-7-9-19(10-8-17)33-24(25,26)27)18-12-15-6-11-20(14-16(15)13-18)34-23(2,3)21(30)31/h6-11,14,18H,5,12-13H2,1-4H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Curated by ChEMBL					Assay Description Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene induction				Bioorg Med Chem Lett 17: 6773-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.041 BindingDB Entry DOI: 10.7270/Q27945H6
					More data for this Ligand-Target Pair