BDBM50227756 2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)methyl)phenoxy)phenoxy)propanoic acid::CHEMBL393940

SMILES: Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O

InChI Key: InChIKey=LVTFMCYHAXZDHY-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50227756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdelta				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalpha				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgamma				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50227756 (2-methyl-2-(2-methyl-4-(3-((2-methylbenzamido)meth...) Show SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccccc3C)c2)ccc1OC(C)(C)C(O)=O Show InChI InChI=1S/C26H27NO5/c1-17-8-5-6-11-22(17)24(28)27-16-19-9-7-10-20(15-19)31-21-12-13-23(18(2)14-21)32-26(3,4)25(29)30/h5-15H,16H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair