BDBM50230585 CHEMBL9856
SMILES: COc1ccnc(C[S+]([O-])c2nc3cc(OCC(F)(F)F)ccc3[nH]2)c1C
InChI Key: InChIKey=JAJVJKRIHGUXJX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Potassium-transporting ATPase alpha chain 1/beta chain (Homo sapiens (Human)) | BDBM50230585 (CHEMBL9856) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals Curated by ChEMBL | Assay Description In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. | J Med Chem 35: 1049-57 (1992) BindingDB Entry DOI: 10.7270/Q2QJ7KJH | |||||||||||
More data for this Ligand-Target Pair |