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SMILES: CC(C)(C)c1ccc(cc1)-c1nc2ccc(OC(F)(F)F)cc2[nH]1

InChI Key: InChIKey=XCKAYKKBMJSIHM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231052   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50231052
PNG
(2-(4-tert-butylphenyl)-5-(trifluoromethoxy)-1H-ben...)
Show SMILES CC(C)(C)c1ccc(cc1)-c1nc2ccc(OC(F)(F)F)cc2[nH]1
Show InChI InChI=1S/C18H17F3N2O/c1-17(2,3)12-6-4-11(5-7-12)16-22-14-9-8-13(10-15(14)23-16)24-18(19,20)21/h4-10H,1-3H3,(H,22,23)
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n/an/a 1.42E+3n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cells

Bioorg Med Chem Lett 18: 1072-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.007
BindingDB Entry DOI: 10.7270/Q2PZ58K9
More data for this
Ligand-Target Pair