BDBM50231526 4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide::CHEMBL253608::N-[(3-chloro-5-(1-piperidinyl)phenyl] 4-[(2-amino)ethoxy]-3,5-dimethylbenzamide

SMILES: Cc1cc(cc(C)c1OCCN)C(=O)Nc1cc(Cl)cc(c1)N1CCCCC1

InChI Key: InChIKey=JDYIYIRPQKMWMM-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50231526 (4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphen...) Show SMILES Cc1cc(cc(C)c1OCCN)C(=O)Nc1cc(Cl)cc(c1)N1CCCCC1 Show InChI InChI=1S/C22H28ClN3O2/c1-15-10-17(11-16(2)21(15)28-9-6-24)22(27)25-19-12-18(23)13-20(14-19)26-7-4-3-5-8-26/h10-14H,3-9,24H2,1-2H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Astex Therapeutics Ltd Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 51: 183-6 (2008) Article DOI: 10.1021/jm701359z BindingDB Entry DOI: 10.7270/Q2XG9QWK
					More data for this Ligand-Target Pair				3D Structure (crystal)