BDBM50231802 CHEMBL4078150

SMILES: Cc1ccc(cc1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key: InChIKey=CPVFJDIGIVKEBO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Homo sapiens (Human))	BDBM50231802 (CHEMBL4078150) Show SMILES Cc1ccc(cc1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C13H11F3N2O2S/c1-8-3-5-9(6-4-8)10-7-11(13(14,15)16)18-12(17-10)21(2,19)20/h3-7H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...				ACS Med Chem Lett 8: 407-412 (2017) BindingDB Entry DOI: 10.7270/Q29Z9745
					More data for this Ligand-Target Pair