null

SMILES: COc1cc(ccc1Nc1ncc2c(C)cc(=O)n([C@H]3CCN(C3)C(=O)C=C)c2n1)N1CCN(C)CC1

InChI Key: InChIKey=UBQLTEZUAMOROQ-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM50234187 (CHEMBL4093766) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n([C@H]3CCN(C3)C(=O)C=C)c2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C27H33N7O3/c1-5-24(35)33-9-8-20(17-33)34-25(36)14-18(2)21-16-28-27(30-26(21)34)29-22-7-6-19(15-23(22)37-4)32-12-10-31(3)11-13-32/h5-7,14-16,20H,1,8-13,17H2,2-4H3,(H,28,29,30)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50234187 (CHEMBL4093766) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n([C@H]3CCN(C3)C(=O)C=C)c2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C27H33N7O3/c1-5-24(35)33-9-8-20(17-33)34-25(36)14-18(2)21-16-28-27(30-26(21)34)29-22-7-6-19(15-23(22)37-4)32-12-10-31(3)11-13-32/h5-7,14-16,20H,1,8-13,17H2,2-4H3,(H,28,29,30)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 126: 1107-1117 (2017) BindingDB Entry DOI: 10.7270/Q2F47RD5
					More data for this Ligand-Target Pair