BDBM50235654 CHEMBL4086916

SMILES: CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1C1CC1

InChI Key: InChIKey=SPISXQLWDSIXOK-WBMJQRKESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (EED) (Homo sapiens (Human))	BDBM50235654 (CHEMBL4086916) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1C1CC1 |r| Show InChI InChI=1S/C16H22BrFN2/c1-19(2)16-10-20(8-12(16)11-6-7-11)9-13-14(17)4-3-5-15(13)18/h3-5,11-12,16H,6-10H2,1-2H3/t12-,16+/m1/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay				Bioorg Med Chem Lett 27: 1576-1583 (2017) Article DOI: 10.1016/j.bmcl.2017.02.030 BindingDB Entry DOI: 10.7270/Q22F7QQG
					More data for this Ligand-Target Pair