BDBM50235968 CHEMBL4069468

SMILES: C[C@@H]1CN([C@@H](CO1)c1ccccc1F)c1cc2NC(=O)COc2cn1

InChI Key: InChIKey=BIWXPKQNQLRCJF-ABAIWWIYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50235968 (CHEMBL4069468) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1F)c1cc2NC(=O)COc2cn1 |r| Show InChI InChI=1S/C18H18FN3O3/c1-11-8-22(15(9-24-11)12-4-2-3-5-13(12)19)17-6-14-16(7-20-17)25-10-18(23)21-14/h2-7,11,15H,8-10H2,1H3,(H,21,23)/t11-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Antagonist activity at Gal4-fused MR LBD (unknown origin) expressed in human Huh7 cells assessed as inhibition of aldosterone-induced transcriptional...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair