BDBM50236055 CHEMBL254172::rac-3-(2-(1-(3,4-difluorophenyl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide

SMILES: CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(F)c1

InChI Key: InChIKey=PJBCNDYSDXMUJE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236055 (CHEMBL254172 | rac-3-(2-(1-(3,4-difluorophenyl)pro...) Show SMILES CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(F)c1 |w:2.2| Show InChI InChI=1S/C22H21F2N3O4/c1-4-15(11-8-9-13(23)14(24)10-11)25-17-18(21(30)20(17)29)26-16-7-5-6-12(19(16)28)22(31)27(2)3/h5-10,15,25-26,28H,4H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 by SPA assay				Bioorg Med Chem Lett 18: 1864-8 (2008) Article DOI: 10.1016/j.bmcl.2008.02.010 BindingDB Entry DOI: 10.7270/Q2CC10DK
					More data for this Ligand-Target Pair