BDBM50236248 7-[(1E)-(ethoxyimino)methyl]-19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one::CHEMBL257788

SMILES: CCO\N=C\c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1

InChI Key: InChIKey=LFLAFTJOXJJWMU-YCPBAFNGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50236248 (7-[(1E)-(ethoxyimino)methyl]-19-methyl-3,13,19,20-...) Show SMILES CCO\N=C\c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C23H21N5O2/c1-3-30-25-9-12-4-6-17-14(8-12)20-15-10-24-23(29)21(15)19-13(22(20)26-17)5-7-18-16(19)11-28(2)27-18/h4,6,8-9,11,26H,3,5,7,10H2,1-2H3,(H,24,29)/b25-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236248 (7-[(1E)-(ethoxyimino)methyl]-19-methyl-3,13,19,20-...) Show SMILES CCO\N=C\c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C23H21N5O2/c1-3-30-25-9-12-4-6-17-14(8-12)20-15-10-24-23(29)21(15)19-13(22(20)26-17)5-7-18-16(19)11-28(2)27-18/h4,6,8-9,11,26H,3,5,7,10H2,1-2H3,(H,24,29)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair