BDBM50236568 CHEMBL4103565

SMILES: FC(F)(F)c1ccc(cc1)-c1noc(CCCBr)n1

InChI Key: InChIKey=DGLUXCRXGXTWME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50236568 (CHEMBL4103565) Show SMILES FC(F)(F)c1ccc(cc1)-c1noc(CCCBr)n1 Show InChI InChI=1S/C12H10BrF3N2O/c13-7-1-2-10-17-11(18-19-10)8-3-5-9(6-4-8)12(14,15)16/h3-6H,1-2,7H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bayreuth Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherichia coli using ...				J Med Chem 60: 2344-2360 (2017) Article DOI: 10.1021/acs.jmedchem.6b01609 BindingDB Entry DOI: 10.7270/Q2J968NS
					More data for this Ligand-Target Pair