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SMILES: Cc1ccc(OCC(=O)N\N=C\c2c[nH]nc2-c2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=NHIKNDVPVKSLFG-LSFURLLWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50237239
PNG
(CHEMBL3192431)
Show SMILES Cc1ccc(OCC(=O)N\N=C\c2c[nH]nc2-c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C19H16Cl2N4O2/c1-12-2-5-15(6-3-12)27-11-18(26)24-22-9-14-10-23-25-19(14)13-4-7-16(20)17(21)8-13/h2-10H,11H2,1H3,(H,23,25)(H,24,26)/b22-9+
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Article
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n/an/a 3.09E+4n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...

Bioorg Med Chem Lett 27: 1776-1779 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.060
BindingDB Entry DOI: 10.7270/Q2H41TQC
More data for this
Ligand-Target Pair