BDBM50239442 CHEMBL3134587
SMILES: FC(F)(F)C(=O)Nc1sc2CCCCCc2c1C(=O)Nc1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=PNKMMVOTUMCION-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239442 (CHEMBL3134587) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair |