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SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1C(F)(F)F

InChI Key: InChIKey=QNRBMZWXRVJBNI-SANMLTNESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240767 (CHEMBL4092280) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C28H23F3N4O/c1-17-22-13-19(11-12-25(22)35-34-17)23-14-20(33-26(16-36)18-7-3-2-4-8-18)15-32-27(23)21-9-5-6-10-24(21)28(29,30)31/h2-15,26,33,36H,16H2,1H3,(H,34,35)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50240767 (CHEMBL4092280) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C28H23F3N4O/c1-17-22-13-19(11-12-25(22)35-34-17)23-14-20(33-26(16-36)18-7-3-2-4-8-18)15-32-27(23)21-9-5-6-10-24(21)28(29,30)31/h2-15,26,33,36H,16H2,1H3,(H,34,35)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50240767 (CHEMBL4092280) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C28H23F3N4O/c1-17-22-13-19(11-12-25(22)35-34-17)23-14-20(33-26(16-36)18-7-3-2-4-8-18)15-32-27(23)21-9-5-6-10-24(21)28(29,30)31/h2-15,26,33,36H,16H2,1H3,(H,34,35)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair