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SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(NCCO)cnc1-c1cc(F)ccc1O

InChI Key: InChIKey=XBRPPAQWEPQQQL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50240795 (CHEMBL4100109) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(NCCO)cnc1-c1cc(F)ccc1O Show InChI InChI=1S/C21H19FN4O2/c1-12-16-8-13(2-4-19(16)26-25-12)17-10-15(23-6-7-27)11-24-21(17)18-9-14(22)3-5-20(18)28/h2-5,8-11,23,27-28H,6-7H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50240795 (CHEMBL4100109) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(NCCO)cnc1-c1cc(F)ccc1O Show InChI InChI=1S/C21H19FN4O2/c1-12-16-8-13(2-4-19(16)26-25-12)17-10-15(23-6-7-27)11-24-21(17)18-9-14(22)3-5-20(18)28/h2-5,8-11,23,27-28H,6-7H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240795 (CHEMBL4100109) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(NCCO)cnc1-c1cc(F)ccc1O Show InChI InChI=1S/C21H19FN4O2/c1-12-16-8-13(2-4-19(16)26-25-12)17-10-15(23-6-7-27)11-24-21(17)18-9-14(22)3-5-20(18)28/h2-5,8-11,23,27-28H,6-7H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair