BDBM50242652 CHEMBL4084742

SMILES: CCOC(=O)CC1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O

InChI Key: InChIKey=SQZMNUCOCYZXAL-SREVYHEPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242652 (CHEMBL4084742) Show SMILES CCOC(=O)CC1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C20H25N3O5/c1-2-28-19(26)12-14-8-10-23(11-9-14)18(25)7-6-17(24)22-16-5-3-4-15(13-16)20(21)27/h3-7,13-14H,2,8-12H2,1H3,(H2,21,27)(H,22,24)/b7-6-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242652 (CHEMBL4084742) Show SMILES CCOC(=O)CC1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C20H25N3O5/c1-2-28-19(26)12-14-8-10-23(11-9-14)18(25)7-6-17(24)22-16-5-3-4-15(13-16)20(21)27/h3-7,13-14H,2,8-12H2,1H3,(H2,21,27)(H,22,24)/b7-6-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair