BDBM50242655 CHEMBL4080281

SMILES: NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CCc3ccccc3)CC2)c1

InChI Key: InChIKey=ULHCPLHSELMUEW-QXMHVHEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242655 (CHEMBL4080281) Show SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CCc3ccccc3)CC2)c1 Show InChI InChI=1S/C24H27N3O3/c25-24(30)20-7-4-8-21(17-20)26-22(28)11-12-23(29)27-15-13-19(14-16-27)10-9-18-5-2-1-3-6-18/h1-8,11-12,17,19H,9-10,13-16H2,(H2,25,30)(H,26,28)/b12-11-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242655 (CHEMBL4080281) Show SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CCc3ccccc3)CC2)c1 Show InChI InChI=1S/C24H27N3O3/c25-24(30)20-7-4-8-21(17-20)26-22(28)11-12-23(29)27-15-13-19(14-16-27)10-9-18-5-2-1-3-6-18/h1-8,11-12,17,19H,9-10,13-16H2,(H2,25,30)(H,26,28)/b12-11-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	676	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair