BDBM50242929 (S)-2-amino-3-(4-(5-((9-ethyl-9H-carbazol-3-yl)methylamino)pyrazin-2-yl)phenyl)propanoic acid::CHEMBL469463

SMILES: CCn1c2ccccc2c2cc(CNc3cnc(cn3)-c3ccc(C[C@H](N)C(O)=O)cc3)ccc12

InChI Key: InChIKey=LEGHNPRYLKPGTM-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50242929 ((S)-2-amino-3-(4-(5-((9-ethyl-9H-carbazol-3-yl)met...) Show SMILES CCn1c2ccccc2c2cc(CNc3cnc(cn3)-c3ccc(C[C@H](N)C(O)=O)cc3)ccc12 |r| Show InChI InChI=1S/C28H27N5O2/c1-2-33-25-6-4-3-5-21(25)22-13-19(9-12-26(22)33)15-31-27-17-30-24(16-32-27)20-10-7-18(8-11-20)14-23(29)28(34)35/h3-13,16-17,23H,2,14-15,29H2,1H3,(H,31,32)(H,34,35)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM
					More data for this Ligand-Target Pair