BDBM50244077 4-(((3-chloro-4-(4-chlorophenoxy)phenyl)(4-phenylthiazol-2-yl)amino)methyl)-N-(1H-tetrazol-5-yl)benzamide::CHEMBL503919

SMILES: Clc1ccc(Oc2ccc(cc2Cl)N(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2nc(cs2)-c2ccccc2)cc1

InChI Key: InChIKey=RFUJVVZCTSUHLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50244077 (4-(((3-chloro-4-(4-chlorophenoxy)phenyl)(4-phenylt...) Show SMILES Clc1ccc(Oc2ccc(cc2Cl)N(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2nc(cs2)-c2ccccc2)cc1 Show InChI InChI=1S/C30H21Cl2N7O2S/c31-22-10-13-24(14-11-22)41-27-15-12-23(16-25(27)32)39(30-33-26(18-42-30)20-4-2-1-3-5-20)17-19-6-8-21(9-7-19)28(40)34-29-35-37-38-36-29/h1-16,18H,17H2,(H2,34,35,36,37,38,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
					More data for this Ligand-Target Pair