BDBM50244093 1-hydroxypropane-1,2,3-tricarboxylate::isocitrate::isocitrate(3-)
SMILES: OC(C(CC([O-])=O)C([O-])=O)C([O-])=O
InChI Key: InChIKey=ODBLHEXUDAPZAU-UHFFFAOYSA-K
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Bacillus licheniformis) | BDBM50244093 (1-hydroxypropane-1,2,3-tricarboxylate | isocitrate...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
Universit£ Catholique de Louvain Curated by ChEMBL | Assay Description Inhibition of Bacillus licheniformis BS3 beta-lactamase at pH 5 | Bioorg Med Chem Lett 19: 3593-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.149 BindingDB Entry DOI: 10.7270/Q2W9597J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Egl nine homolog 1 (Homo sapiens (Human)) | BDBM50244093 (1-hydroxypropane-1,2,3-tricarboxylate | isocitrate...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of PHD2 (unknown origin) | J Med Chem 56: 547-55 (2013) Article DOI: 10.1021/jm301583m BindingDB Entry DOI: 10.7270/Q26Q1ZJV | |||||||||||
More data for this Ligand-Target Pair |