BDBM50244339 CHEMBL469904::trans-N-((1H-tetrazol-5-yl)methyl)-4-(((4-tert-butylcyclohexyl)(1-methyl-1H-benzo[d]imidazol-2-yl)amino)methyl)benzamide

SMILES: Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)NCc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C

InChI Key: InChIKey=WOCOPPOJDSBENE-HZCBDIJESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50244339 (CHEMBL469904 | trans-N-((1H-tetrazol-5-yl)methyl)-...) Show SMILES Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)NCc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C |r,wU:27.30,wD:30.37,(-6.06,-.47,;-5.29,.86,;-3.86,1.45,;-3.99,2.99,;-5.49,3.34,;-6.22,4.69,;-7.76,4.73,;-8.56,3.41,;-7.82,2.06,;-6.29,2.03,;-2.53,.67,;-2.54,-.87,;-1.21,-1.65,;.12,-.88,;1.45,-1.65,;1.44,-3.2,;.09,-3.96,;-1.23,-3.18,;2.77,-3.97,;2.76,-5.51,;4.11,-3.21,;5.44,-3.99,;6.78,-3.23,;8.24,-3.69,;9.14,-2.44,;8.23,-1.2,;6.77,-1.68,;-1.2,1.43,;-1.2,2.97,;.15,3.73,;1.47,2.95,;1.46,1.41,;.12,.65,;2.82,3.71,;4.14,4.49,;3.59,2.37,;2.05,5.04,)| Show InChI InChI=1S/C28H36N8O/c1-28(2,3)21-13-15-22(16-14-21)36(27-30-23-7-5-6-8-24(23)35(27)4)18-19-9-11-20(12-10-19)26(37)29-17-25-31-33-34-32-25/h5-12,21-22H,13-18H2,1-4H3,(H,29,37)(H,31,32,33,34)/t21-,22-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
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