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SMILES: Cc1ccc(cc1NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=NZCFIQMFQCSIJL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244630   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50244630
PNG
(CHEMBL454105 | N-(2-methyl-5-((3-(trifluoromethyl)...)
Show SMILES Cc1ccc(cc1NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H16F3N3O2/c1-13-7-8-14(10-18(13)27-20(29)15-4-3-9-25-12-15)19(28)26-17-6-2-5-16(11-17)21(22,23)24/h2-12H,1H3,(H,26,28)(H,27,29)
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Article
PubMed
n/an/a 32n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of CSF1R (unknown origin)

Bioorg Med Chem Lett 18: 4794-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.093
BindingDB Entry DOI: 10.7270/Q2028RCC
More data for this
Ligand-Target Pair