BDBM50244665 CHEMBL4097332

SMILES: CN(C)c1ccc(cn1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O

InChI Key: InChIKey=GCQRNJUDAAOEJK-UHFFFAOYSA-N

Data: 1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase Complex 1 (Homo sapiens (Human))	BDBM50244665 (CHEMBL4097332) Show SMILES CN(C)c1ccc(cn1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C16H14ClN3O2/c1-20(2)15-4-3-9(7-19-15)10-5-11-12(16(21)22)8-18-14(11)6-13(10)17/h3-8,18H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Allosteric activation of human AMPK alpha1/beta1/gamma1 by TR-FRET assay				J Med Chem 61: 2372-2383 (2018) Article DOI: 10.1021/acs.jmedchem.7b01641 BindingDB Entry DOI: 10.7270/Q2028TZT
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase Complex 1 (Homo sapiens (Human))	BDBM50244665 (CHEMBL4097332) Show SMILES CN(C)c1ccc(cn1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C16H14ClN3O2/c1-20(2)15-4-3-9(7-19-15)10-5-11-12(16(21)22)8-18-14(11)6-13(10)17/h3-8,18H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human BAP-tagged AMPK alpha1/beta1/gamma1 by SPR assay				J Med Chem 61: 2372-2383 (2018) Article DOI: 10.1021/acs.jmedchem.7b01641 BindingDB Entry DOI: 10.7270/Q2028TZT
					More data for this Ligand-Target Pair