null

SMILES: CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(nc1C)C(F)(F)F

InChI Key: InChIKey=ORQMKFFCOVXYBG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-like protein 1/NEDD8-conjugating enzyme Ubc12 (Homo sapiens)	BDBM50245230 (CHEMBL4086530 | US11116757, No. A178) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(nc1C)C(F)(F)F Show InChI InChI=1S/C25H33F3N4O/c1-4-8-18(2)31-15-13-21(14-16-31)32(17-20-9-6-5-7-10-20)24(33)30-22-11-12-23(25(26,27)28)29-19(22)3/h5-7,9-12,18,21H,4,8,13-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245230 (CHEMBL4086530 | US11116757, No. A178) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(nc1C)C(F)(F)F Show InChI InChI=1S/C25H33F3N4O/c1-4-8-18(2)31-15-13-21(14-16-31)32(17-20-9-6-5-7-10-20)24(33)30-22-11-12-23(25(26,27)28)29-19(22)3/h5-7,9-12,18,21H,4,8,13-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair