null

SMILES: COc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1

InChI Key: InChIKey=ZVFFOXHNUDSYBD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50246543 (CHEMBL4087615) Show SMILES COc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1 Show InChI InChI=1S/C24H24N4O2/c1-29-20-3-5-21(6-4-20)30-24-10-13-26-23-14-17(2-7-22(23)24)18-15-27-28(16-18)19-8-11-25-12-9-19/h2-7,10,13-16,19,25H,8-9,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Inhibition of human ERG by fluorescently labeled tracer binding method				J Med Chem 60: 9205-9221 (2017) Article DOI: 10.1021/acs.jmedchem.7b01039 BindingDB Entry DOI: 10.7270/Q26D5WF3
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50246543 (CHEMBL4087615) Show SMILES COc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1 Show InChI InChI=1S/C24H24N4O2/c1-29-20-3-5-21(6-4-20)30-24-10-13-26-23-14-17(2-7-22(23)24)18-15-27-28(16-18)19-8-11-25-12-9-19/h2-7,10,13-16,19,25H,8-9,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...				J Med Chem 60: 9205-9221 (2017) Article DOI: 10.1021/acs.jmedchem.7b01039 BindingDB Entry DOI: 10.7270/Q26D5WF3
					More data for this Ligand-Target Pair