BDBM50246918 CHEMBL4091369

SMILES: Cl.OC(=O)[C@H]1NCC[C@@H]1c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=PNGCYMVQRLUJQX-UXQCFNEQSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50246918 (CHEMBL4091369) Show SMILES Cl.OC(=O)[C@H]1NCC[C@@H]1c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H12F3NO2.ClH/c13-12(14,15)8-3-1-2-7(6-8)9-4-5-16-10(9)11(17)18;/h1-3,6,9-10,16H,4-5H2,(H,17,18);1H/t9-,10+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]-KA from recombinant homomeric rat GluK2 (V,C,R)a receptor expressed in baculovirus infected Sf9 insect cell membranes by scintil...				J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50246918 (CHEMBL4091369) Show SMILES Cl.OC(=O)[C@H]1NCC[C@@H]1c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H12F3NO2.ClH/c13-12(14,15)8-3-1-2-7(6-8)9-4-5-16-10(9)11(17)18;/h1-3,6,9-10,16H,4-5H2,(H,17,18);1H/t9-,10+;/m1./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]-KA from recombinant homomeric rat GluK3a receptor expressed in baculovirus infected Sf9 insect cell membranes by scintillation c...				J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50246918 (CHEMBL4091369) Show SMILES Cl.OC(=O)[C@H]1NCC[C@@H]1c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H12F3NO2.ClH/c13-12(14,15)8-3-1-2-7(6-8)9-4-5-16-10(9)11(17)18;/h1-3,6,9-10,16H,4-5H2,(H,17,18);1H/t9-,10+;/m1./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]-SYM2081 from recombinant homomeric rat GluK1 (Q)1b receptor expressed in baculovirus infected Sf9 insect cell membranes by scint...				J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD
					More data for this Ligand-Target Pair