BDBM50247464 6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphenyl)-3-methyl-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::CHEMBL517444::cid_2947766

SMILES: COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1

InChI Key: InChIKey=ZAGGUJPGHQAIGW-UHFFFAOYSA-N

Data: 2 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50247464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2NZ862K
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	>4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Florida Atlantic University Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 expressed in Escherichia coli				Bioorg Med Chem 17: 990-1005 (2009) Article DOI: 10.1016/j.bmc.2008.03.004 BindingDB Entry DOI: 10.7270/Q2GB24ZC
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2JW8C95
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2J67FB5
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50247464 (6-amino-1-(3-bromo-2-chloro-4-hydroxy-5-methoxyphe...) Show SMILES COc1cc(c(Cl)c(Br)c1O)-n1nc(C)c2C(C(C#N)C(=N)Oc12)c1ccccc1 Show InChI InChI=1S/C21H16BrClN4O3/c1-10-15-16(11-6-4-3-5-7-11)12(9-24)20(25)30-21(15)27(26-10)13-8-14(29-2)19(28)17(22)18(13)23/h3-8,12,16,25,28H,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair