null
SMILES: Cc1oc(nc1CCOc1ccc(Cc2nn(nc2CC(O)=O)-c2ccccc2)cc1)-c1ccccc1
InChI Key: InChIKey=SEODTXMDIACADJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50248463![]() (2-(5-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Binding affinity to PPARalpha (unknown origin) by fluorescence polarization assay | Bioorg Med Chem Lett 19: 1451-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.030 BindingDB Entry DOI: 10.7270/Q2MC8ZW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50248463![]() (2-(5-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in HEK293 cells by Gal4 transactivation assay | Bioorg Med Chem Lett 19: 1451-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.030 BindingDB Entry DOI: 10.7270/Q2MC8ZW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50248463![]() (2-(5-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Binding affinity to PPARgamma (unknown origin) by fluorescence polarization assay | Bioorg Med Chem Lett 19: 1451-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.030 BindingDB Entry DOI: 10.7270/Q2MC8ZW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50248463![]() (2-(5-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in HEK293 cells by Gal4 transactivation assay | Bioorg Med Chem Lett 19: 1451-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.030 BindingDB Entry DOI: 10.7270/Q2MC8ZW8 | |||||||||||
More data for this Ligand-Target Pair |