BDBM50251322 CHEMBL4076617

SMILES: Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3n(C)ccc23)c(F)c1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=KLBRHXOKSPCITH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50251322 (CHEMBL4076617) Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3n(C)ccc23)c(F)c1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H19F4N5O3/c1-15-12-23(37)36(18-5-3-4-16(13-18)27(29,30)31)34-24(15)26(38)33-17-6-7-22(20(28)14-17)39-21-8-10-32-25-19(21)9-11-35(25)2/h3-14H,1-2H3,(H,33,38)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com. Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Eur J Med Chem 133: 97-106 (2017) Article DOI: 10.1016/j.ejmech.2017.03.045 BindingDB Entry DOI: 10.7270/Q2K35X3B
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