Found 5 hits for monomerid = 50251467 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50251467
((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(3-nitropyridi...)Show SMILES [O-][N+](=O)c1cccnc1N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C17H19FN6O3/c18-10-4-11(5-19)23(7-10)15(25)6-21-16-12-8-22(9-13(12)16)17-14(24(26)27)2-1-3-20-17/h1-3,10-13,16,21H,4,6-9H2/t10-,11-,12-,13+,16+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human plasma DPP4 |
Bioorg Med Chem Lett 18: 4087-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2
(Homo sapiens (Human)) | BDBM50251467
((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(3-nitropyridi...)Show SMILES [O-][N+](=O)c1cccnc1N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C17H19FN6O3/c18-10-4-11(5-19)23(7-10)15(25)6-21-16-12-8-22(9-13(12)16)17-14(24(26)27)2-1-3-20-17/h1-3,10-13,16,21H,4,6-9H2/t10-,11-,12-,13+,16+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP2 (unknown origin) |
Bioorg Med Chem Lett 18: 4087-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC |
More data for this Ligand-Target Pair | |
Prolyl endopeptidase
(Homo sapiens (Human)) | BDBM50251467
((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(3-nitropyridi...)Show SMILES [O-][N+](=O)c1cccnc1N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C17H19FN6O3/c18-10-4-11(5-19)23(7-10)15(25)6-21-16-12-8-22(9-13(12)16)17-14(24(26)27)2-1-3-20-17/h1-3,10-13,16,21H,4,6-9H2/t10-,11-,12-,13+,16+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PPCE (unknown origin) |
Bioorg Med Chem Lett 18: 4087-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50251467
((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(3-nitropyridi...)Show SMILES [O-][N+](=O)c1cccnc1N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C17H19FN6O3/c18-10-4-11(5-19)23(7-10)15(25)6-21-16-12-8-22(9-13(12)16)17-14(24(26)27)2-1-3-20-17/h1-3,10-13,16,21H,4,6-9H2/t10-,11-,12-,13+,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 525 | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP9 (unknown origin) |
Bioorg Med Chem Lett 18: 4087-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50251467
((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(3-nitropyridi...)Show SMILES [O-][N+](=O)c1cccnc1N1C[C@H]2[C@@H](C1)[C@@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C17H19FN6O3/c18-10-4-11(5-19)23(7-10)15(25)6-21-16-12-8-22(9-13(12)16)17-14(24(26)27)2-1-3-20-17/h1-3,10-13,16,21H,4,6-9H2/t10-,11-,12-,13+,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP8 (unknown origin) |
Bioorg Med Chem Lett 18: 4087-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC |
More data for this Ligand-Target Pair | |