BDBM50252042 (+/-)-N-(1-(3-methyl-4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide::CHEMBL480778

SMILES: CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1C

InChI Key: InChIKey=XZXBMHKXPUBQEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50252042 ((+/-)-N-(1-(3-methyl-4-(1-methylpyrrolidin-3-yloxy...) Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1C Show InChI InChI=1S/C24H29Cl2N3O2/c1-16-11-17(3-6-23(16)31-20-8-9-28(2)15-20)13-29-10-7-19(14-29)27-24(30)18-4-5-21(25)22(26)12-18/h3-6,11-12,19-20H,7-10,13-15H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair