BDBM50253546 3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]pyridine::CHEMBL494713

SMILES: COc1ccc(Cc2cc3cc(OC)ccc3cc2-c2cccnc2)cc1

InChI Key: InChIKey=VQUARJCMNGAQJX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50253546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50253546 (3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]py...) Show SMILES COc1ccc(Cc2cc3cc(OC)ccc3cc2-c2cccnc2)cc1 Show InChI InChI=1S/C24H21NO2/c1-26-22-8-5-17(6-9-22)12-21-13-20-14-23(27-2)10-7-18(20)15-24(21)19-4-3-11-25-16-19/h3-11,13-16H,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cells				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50253546 (3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]py...) Show SMILES COc1ccc(Cc2cc3cc(OC)ccc3cc2-c2cccnc2)cc1 Show InChI InChI=1S/C24H21NO2/c1-26-22-8-5-17(6-9-22)12-21-13-20-14-23(27-2)10-7-18(20)15-24(21)19-4-3-11-25-16-19/h3-11,13-16H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomes				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50253546 (3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]py...) Show SMILES COc1ccc(Cc2cc3cc(OC)ccc3cc2-c2cccnc2)cc1 Show InChI InChI=1S/C24H21NO2/c1-26-22-8-5-17(6-9-22)12-21-13-20-14-23(27-2)10-7-18(20)15-24(21)19-4-3-11-25-16-19/h3-11,13-16H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental microsome CYP19				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50253546 (3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]py...) Show SMILES COc1ccc(Cc2cc3cc(OC)ccc3cc2-c2cccnc2)cc1 Show InChI InChI=1S/C24H21NO2/c1-26-22-8-5-17(6-9-22)12-21-13-20-14-23(27-2)10-7-18(20)15-24(21)19-4-3-11-25-16-19/h3-11,13-16H,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cells				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair