BDBM50253553 CHEMBL494116::endo-8-(1H-Indol-3-ylmethyl)-3-(2-naphthyl)-8-azabicyclo[3.2.1]octan-3-ol

SMILES: OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc2ccccc2c1

InChI Key: InChIKey=YJKBKDOYRHHENB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50253553 (CHEMBL494116 | endo-8-(1H-Indol-3-ylmethyl)-3-(2-n...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc2ccccc2c1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C26H26N2O/c29-26(21-10-9-18-5-1-2-6-19(18)13-21)14-22-11-12-23(15-26)28(22)17-20-16-27-25-8-4-3-7-24(20)25/h1-10,13,16,22-23,27,29H,11-12,14-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	196	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50253553 (CHEMBL494116 | endo-8-(1H-Indol-3-ylmethyl)-3-(2-n...) Show SMILES OC1(CC2CCC(C1)N2Cc1c[nH]c2ccccc12)c1ccc2ccccc2c1 |TLB:9:8:4.5:2.1.7,0:1:4.5:8,THB:19:1:4.5:8| Show InChI InChI=1S/C26H26N2O/c29-26(21-10-9-18-5-1-2-6-19(18)13-21)14-22-11-12-23(15-26)28(22)17-20-16-27-25-8-4-3-7-24(20)25/h1-10,13,16,22-23,27,29H,11-12,14-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuses Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 6095-109 (2008) Article DOI: 10.1021/jm800532x BindingDB Entry DOI: 10.7270/Q2HM589Q
					More data for this Ligand-Target Pair