null

SMILES: Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12

InChI Key: InChIKey=JRVIABLHHDFKSO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assay				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair