BDBM50255856 2-amino-N-(4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)phenyl)benzamide::CHEMBL480730

SMILES: Nc1ccccc1C(=O)Nc1ccc(CNc2nccc(n2)-c2cccnc2)cc1

InChI Key: InChIKey=MKZLPXBFXXXRSF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50255856 (2-amino-N-(4-((4-(pyridin-3-yl)pyrimidin-2-ylamino...) Show SMILES Nc1ccccc1C(=O)Nc1ccc(CNc2nccc(n2)-c2cccnc2)cc1 Show InChI InChI=1S/C23H20N6O/c24-20-6-2-1-5-19(20)22(30)28-18-9-7-16(8-10-18)14-27-23-26-13-11-21(29-23)17-4-3-12-25-15-17/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1				Bioorg Med Chem Lett 19: 644-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.048 BindingDB Entry DOI: 10.7270/Q2PN95J1
					More data for this Ligand-Target Pair