BDBM50257254 2-{1-[3-(5-Benzoyl-1-propyl-naphthalen-2-yloxy)-propyl]-1H-indol-5-yloxy}-2-methyl-propionicacid::CHEMBL454508

SMILES: CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2c(cccc12)C(=O)c1ccccc1

InChI Key: InChIKey=KDCLRVJGUDZHRK-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50257254 (2-{1-[3-(5-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2c(cccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C35H35NO5/c1-4-10-29-27-13-8-14-30(33(37)24-11-6-5-7-12-24)28(27)16-18-32(29)40-22-9-20-36-21-19-25-23-26(15-17-31(25)36)41-35(2,3)34(38)39/h5-8,11-19,21,23H,4,9-10,20,22H2,1-3H3,(H,38,39)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50257254 (2-{1-[3-(5-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2c(cccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C35H35NO5/c1-4-10-29-27-13-8-14-30(33(37)24-11-6-5-7-12-24)28(27)16-18-32(29)40-22-9-20-36-21-19-25-23-26(15-17-31(25)36)41-35(2,3)34(38)39/h5-8,11-19,21,23H,4,9-10,20,22H2,1-3H3,(H,38,39)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50257254 (2-{1-[3-(5-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2c(cccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C35H35NO5/c1-4-10-29-27-13-8-14-30(33(37)24-11-6-5-7-12-24)28(27)16-18-32(29)40-22-9-20-36-21-19-25-23-26(15-17-31(25)36)41-35(2,3)34(38)39/h5-8,11-19,21,23H,4,9-10,20,22H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair