BDBM50257512 (S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonamido)-3-(3-carbamimidoylphenyl)propanoyl)piperidin-4-yl)-N-methylbutanamide::CHEMBL444411::US8569313, 32

SMILES: CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key: InChIKey=HWNRARJHWWELBD-VWLOTQADSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50257512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition assay using matriptase enzyme				US Patent US8569313 (2013) BindingDB Entry DOI: 10.7270/Q2639ND5
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of matriptase (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of uPA (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50257512 ((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...) Show SMILES CNC(=O)CCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C29H41N7O5S/c1-33-26(37)10-3-5-20-12-15-36(16-13-20)29(39)25(18-21-6-2-7-22(17-21)28(31)32)35-42(40,41)24-9-4-8-23(19-24)34-27(38)11-14-30/h2,4,6-9,17,19-20,25,35H,3,5,10-16,18,30H2,1H3,(H3,31,32)(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair