BDBM50258793 4-(1H-indol-7-ylamino)-5-(3,4-dimethoxyphenyl)nicotinonitrile::CHEMBL511716

SMILES: COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2cc[nH]c12

InChI Key: InChIKey=KIVCDAJCNFMMGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258793 (4-(1H-indol-7-ylamino)-5-(3,4-dimethoxyphenyl)nico...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2cc[nH]c12 Show InChI InChI=1S/C22H18N4O2/c1-27-19-7-6-15(10-20(19)28-2)17-13-24-12-16(11-23)21(17)26-18-5-3-4-14-8-9-25-22(14)18/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair