BDBM50258955 CHEMBL4075125

SMILES: [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O

InChI Key: InChIKey=QDVDTASXZDDPJL-ZHECQJHESA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Mus musculus)	BDBM50258955 (CHEMBL4075125) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C50H64N12O10/c51-41(64)28-36-45(68)60-38(29-63)46(69)59-37(27-32-17-8-3-9-18-32)48(71)62-24-12-21-40(62)49(72)61-23-11-20-39(61)47(70)55-33(19-10-22-54-50(52)53)42(65)56-34(25-30-13-4-1-5-14-30)43(66)57-35(44(67)58-36)26-31-15-6-2-7-16-31/h1-9,13-18,33-40,63H,10-12,19-29H2,(H2,51,64)(H,55,70)(H,56,65)(H,57,66)(H,58,67)(H,59,69)(H,60,68)(H4,52,53,54)/t33-,34-,35-,36-,37-,38-,39-,40+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...				J Med Chem 60: 8103-8114 (2017) Article DOI: 10.1021/acs.jmedchem.7b00856 BindingDB Entry DOI: 10.7270/Q2DN47H1
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50258955 (CHEMBL4075125) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C50H64N12O10/c51-41(64)28-36-45(68)60-38(29-63)46(69)59-37(27-32-17-8-3-9-18-32)48(71)62-24-12-21-40(62)49(72)61-23-11-20-39(61)47(70)55-33(19-10-22-54-50(52)53)42(65)56-34(25-30-13-4-1-5-14-30)43(66)57-35(44(67)58-36)26-31-15-6-2-7-16-31/h1-9,13-18,33-40,63H,10-12,19-29H2,(H2,51,64)(H,55,70)(H,56,65)(H,57,66)(H,58,67)(H,59,69)(H,60,68)(H4,52,53,54)/t33-,34-,35-,36-,37-,38-,39-,40+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...				J Med Chem 60: 8103-8114 (2017) Article DOI: 10.1021/acs.jmedchem.7b00856 BindingDB Entry DOI: 10.7270/Q2DN47H1
					More data for this Ligand-Target Pair
Melanocortin receptor 1 (Mus musculus)	BDBM50258955 (CHEMBL4075125) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C50H64N12O10/c51-41(64)28-36-45(68)60-38(29-63)46(69)59-37(27-32-17-8-3-9-18-32)48(71)62-24-12-21-40(62)49(72)61-23-11-20-39(61)47(70)55-33(19-10-22-54-50(52)53)42(65)56-34(25-30-13-4-1-5-14-30)43(66)57-35(44(67)58-36)26-31-15-6-2-7-16-31/h1-9,13-18,33-40,63H,10-12,19-29H2,(H2,51,64)(H,55,70)(H,56,65)(H,57,66)(H,58,67)(H,59,69)(H,60,68)(H4,52,53,54)/t33-,34-,35-,36-,37-,38-,39-,40+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...				J Med Chem 60: 8103-8114 (2017) Article DOI: 10.1021/acs.jmedchem.7b00856 BindingDB Entry DOI: 10.7270/Q2DN47H1
					More data for this Ligand-Target Pair