BDBM50259087 CHEMBL467716::benzyl 3-(3,4-dichlorobenzylcarbamoyl)-4-(pyridin-3-yloxy)phenylcarbamate
SMILES: Clc1ccc(CNC(=O)c2cc(NC(=O)OCc3ccccc3)ccc2Oc2cccnc2)cc1Cl
InChI Key: InChIKey=YYLZEIUVJBDDJF-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stearoyl-CoA desaturase 1 (Homo sapiens (Human)) | BDBM50259087 (CHEMBL467716 | benzyl 3-(3,4-dichlorobenzylcarbamo...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc Curated by ChEMBL | Assay Description Inhibition of delta(9)-desaturase from human HepG2 cells | Bioorg Med Chem Lett 19: 3050-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.004 BindingDB Entry DOI: 10.7270/Q2W095TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stearoyl-CoA desaturase 1 (SCD1) (Rattus norvegicus (Rat)) | BDBM50259087 (CHEMBL467716 | benzyl 3-(3,4-dichlorobenzylcarbamo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc Curated by ChEMBL | Assay Description Inhibition of rat microsomal delta(9)-desaturase | Bioorg Med Chem Lett 19: 3050-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.004 BindingDB Entry DOI: 10.7270/Q2W095TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid desaturase 1 (Mus musculus) | BDBM50259087 (CHEMBL467716 | benzyl 3-(3,4-dichlorobenzylcarbamo...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc Curated by ChEMBL | Assay Description Inhibition of delta(5)-desaturase in mouse ABMC7 cells by high throughput radioassay | Bioorg Med Chem Lett 19: 3050-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.004 BindingDB Entry DOI: 10.7270/Q2W095TX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid desaturase 2 (Mus musculus) | BDBM50259087 (CHEMBL467716 | benzyl 3-(3,4-dichlorobenzylcarbamo...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc Curated by ChEMBL | Assay Description Inhibition of delta(6)-desaturase in mouse ABMC7 cells by high throughput radioassay | Bioorg Med Chem Lett 19: 3050-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.004 BindingDB Entry DOI: 10.7270/Q2W095TX | |||||||||||
More data for this Ligand-Target Pair |