BDBM50259582 CHEMBL512962::endo-8-(bis(2-chlorophenyl)methyl)-3-(piperidin-2-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES: NC(=O)C1(C[C@H]2CC[C@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)C1CCCCN1

InChI Key: InChIKey=LIGAXKWGEDSCQR-JGUPTHKFSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50259582 (CHEMBL512962 | endo-8-(bis(2-chlorophenyl)methyl)-...) Show SMILES NC(=O)C1(C[C@H]2CC[C@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)C1CCCCN1 |r,TLB:1:3:10:6.7| Show InChI InChI=1S/C26H31Cl2N3O/c27-21-9-3-1-7-19(21)24(20-8-2-4-10-22(20)28)31-17-12-13-18(31)16-26(15-17,25(29)32)23-11-5-6-14-30-23/h1-4,7-10,17-18,23-24,30H,5-6,11-16H2,(H2,29,32)/t17-,18-,23?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50259582 (CHEMBL512962 | endo-8-(bis(2-chlorophenyl)methyl)-...) Show SMILES NC(=O)C1(C[C@H]2CC[C@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)C1CCCCN1 |r,TLB:1:3:10:6.7| Show InChI InChI=1S/C26H31Cl2N3O/c27-21-9-3-1-7-19(21)24(20-8-2-4-10-22(20)28)31-17-12-13-18(31)16-26(15-17,25(29)32)23-11-5-6-14-30-23/h1-4,7-10,17-18,23-24,30H,5-6,11-16H2,(H2,29,32)/t17-,18-,23?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	474	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair