BDBM50260395 CHEMBL495232::N-(2-(5-Methoxycarbonylamino-benzo[b]furan-3-yl)ethyl)cyclopropylcarboxamide

SMILES: COC(=O)Nc1ccc2occ(CCNC(=O)C3CC3)c2c1

InChI Key: InChIKey=KYSCWFKYUJDVHS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melatonin receptor (Homo sapiens (Human))	BDBM50260395 (CHEMBL495232 | N-(2-(5-Methoxycarbonylamino-benzo[...) Show SMILES COC(=O)Nc1ccc2occ(CCNC(=O)C3CC3)c2c1 Show InChI InChI=1S/C16H18N2O4/c1-21-16(20)18-12-4-5-14-13(8-12)11(9-22-14)6-7-17-15(19)10-2-3-10/h4-5,8-10H,2-3,6-7H2,1H3,(H,17,19)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lille Curated by ChEMBL					Assay Description Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 4954-62 (2008) Article DOI: 10.1016/j.bmc.2008.03.036 BindingDB Entry DOI: 10.7270/Q2JM29DN
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM50260395 (CHEMBL495232 | N-(2-(5-Methoxycarbonylamino-benzo[...) Show SMILES COC(=O)Nc1ccc2occ(CCNC(=O)C3CC3)c2c1 Show InChI InChI=1S/C16H18N2O4/c1-21-16(20)18-12-4-5-14-13(8-12)11(9-22-14)6-7-17-15(19)10-2-3-10/h4-5,8-10H,2-3,6-7H2,1H3,(H,17,19)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lille Curated by ChEMBL					Assay Description Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 4954-62 (2008) Article DOI: 10.1016/j.bmc.2008.03.036 BindingDB Entry DOI: 10.7270/Q2JM29DN
					More data for this Ligand-Target Pair