BDBM50260644 4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-1-methyl-propyl}-benzenesulfonamide::CHEMBL495250
SMILES: COc1ccc(cc1)S(=O)(=O)NC(C)CCN1CCN(CC1)c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=ARWQQHFFCBOLCO-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50260644![]() (4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-pipera...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cell membrane | Bioorg Med Chem 16: 5405-12 (2008) Article DOI: 10.1016/j.bmc.2008.04.023 BindingDB Entry DOI: 10.7270/Q2RX9BVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50260644![]() (4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-pipera...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHOK1 cell membrane | Bioorg Med Chem 16: 5405-12 (2008) Article DOI: 10.1016/j.bmc.2008.04.023 BindingDB Entry DOI: 10.7270/Q2RX9BVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50260644![]() (4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-pipera...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cells | Bioorg Med Chem 16: 5405-12 (2008) Article DOI: 10.1016/j.bmc.2008.04.023 BindingDB Entry DOI: 10.7270/Q2RX9BVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50260644![]() (4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-pipera...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHOK1 cell membrane | Bioorg Med Chem 16: 5405-12 (2008) Article DOI: 10.1016/j.bmc.2008.04.023 BindingDB Entry DOI: 10.7270/Q2RX9BVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50260644![]() (4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-pipera...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHOK1 cell membrane | Bioorg Med Chem 16: 5405-12 (2008) Article DOI: 10.1016/j.bmc.2008.04.023 BindingDB Entry DOI: 10.7270/Q2RX9BVH | |||||||||||
More data for this Ligand-Target Pair |