BDBM50260927 CHEMBL4062035

SMILES: N#Cc1cc(c[nH]1)-c1ccncc1

InChI Key: InChIKey=SCVVEPJFSQHKPL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK8/Cyclin C (Homo sapiens (Human))	BDBM50260927 (CHEMBL4062035) Show SMILES N#Cc1cc(c[nH]1)-c1ccncc1 Show InChI InChI=1S/C10H7N3/c11-6-10-5-9(7-13-10)8-1-3-12-4-2-8/h1-5,7,13H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry, Roche Innovation Center Shanghai, Bldg 5, 720 Cailun Road, Shanghai 201203, China. Electronic address: cyrus.han@roche.com. Curated by ChEMBL					Assay Description Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...				Bioorg Med Chem Lett 27: 4488-4492 (2017) Article DOI: 10.1016/j.bmcl.2017.07.080 BindingDB Entry DOI: 10.7270/Q2NP26W9
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