null

SMILES: N[C@@H](Cn1c(=O)c(c2OCC(c3ccccc3F)n2c1=O)-c1ccccc1F)c1ccccc1

InChI Key: InChIKey=SZPPHNMVCBJCRW-HMTLIYDFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50261206 (6-((R)-2-amino-2-phenylethyl)-3,8-bis(2-fluorophen...) Show SMILES N[C@@H](Cn1c(=O)c(c2OCC(c3ccccc3F)n2c1=O)-c1ccccc1F)c1ccccc1 |r,wD:1.0,(7.85,.67,;7.85,2.21,;9.18,2.98,;10.52,2.22,;11.85,3,;11.85,4.54,;13.18,2.22,;13.18,.68,;14.31,-.34,;13.7,-1.74,;12.18,-1.58,;11.16,-2.72,;9.65,-2.4,;8.62,-3.55,;9.1,-5.01,;10.62,-5.33,;11.64,-4.18,;13.15,-4.49,;11.86,-.09,;10.52,.68,;9.19,-.1,;14.51,2.99,;15.84,2.22,;17.17,2.99,;17.17,4.53,;15.83,5.3,;14.5,4.52,;13.16,5.29,;6.52,2.97,;6.52,4.51,;5.18,5.28,;3.85,4.51,;3.86,2.96,;5.19,2.2,)| Show InChI InChI=1S/C26H21F2N3O3/c27-19-12-6-4-10-17(19)22-15-34-25-23(18-11-5-7-13-20(18)28)24(32)30(26(33)31(22)25)14-21(29)16-8-2-1-3-9-16/h1-13,21-22H,14-15,29H2/t21-,22?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair