BDBM50261208 (R)-6-(2,6-difluorobenzyl)-2-(2-amino-2-phenylethyl)-4-(3-methoxyphenyl)-1,2,4-triazine-3,5(2H,4H)-dione::CHEMBL494968

SMILES: COc1cccc(c1)-n1c(=O)c(Cc2c(F)cccc2F)nn(C[C@H](N)c2ccccc2)c1=O

InChI Key: InChIKey=ZUSYMUVSTOUTAU-QFIPXVFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50261208 ((R)-6-(2,6-difluorobenzyl)-2-(2-amino-2-phenylethy...) Show SMILES COc1cccc(c1)-n1c(=O)c(Cc2c(F)cccc2F)nn(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C25H22F2N4O3/c1-34-18-10-5-9-17(13-18)31-24(32)23(14-19-20(26)11-6-12-21(19)27)29-30(25(31)33)15-22(28)16-7-3-2-4-8-16/h2-13,22H,14-15,28H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair