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SMILES: COc1cccc(c1)-c1c(F)n(Cc2c(F)cccc2F)c(=O)n(CCN(C)CCc2ccccn2)c1=O

InChI Key: InChIKey=OXPSFWNPDGNKGD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50261239
PNG
(1-(2,6-difluorobenzyl)-6-fluoro-5-(3-methoxyphenyl...)
Show SMILES COc1cccc(c1)-c1c(F)n(Cc2c(F)cccc2F)c(=O)n(CCN(C)CCc2ccccn2)c1=O
Show InChI InChI=1S/C28H27F3N4O3/c1-33(14-12-20-8-3-4-13-32-20)15-16-34-27(36)25(19-7-5-9-21(17-19)38-2)26(31)35(28(34)37)18-22-23(29)10-6-11-24(22)30/h3-11,13,17H,12,14-16,18H2,1-2H3
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Similars
Article
PubMed
 34n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc

Curated by ChEMBL


Assay Description
Binding affinity at human GnRH receptor

J Med Chem 51: 3331-48 (2008)


Article DOI: 10.1021/jm701249f
BindingDB Entry DOI: 10.7270/Q2KD1XQ0
More data for this
Ligand-Target Pair