Found 4 hits for monomerid = 50261760 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50261760
(4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c16-15(17,18)13-4-2-1-3-12(13)14-9-22(21-20-14)10-5-7-11(8-6-10)25(19,23)24/h1-9H,(H2,19,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA2 by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human)) | BDBM50261760
(4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c16-15(17,18)13-4-2-1-3-12(13)14-9-22(21-20-14)10-5-7-11(8-6-10)25(19,23)24/h1-9H,(H2,19,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA5B by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50261760
(4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c16-15(17,18)13-4-2-1-3-12(13)14-9-22(21-20-14)10-5-7-11(8-6-10)25(19,23)24/h1-9H,(H2,19,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50261760
(4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c16-15(17,18)13-4-2-1-3-12(13)14-9-22(21-20-14)10-5-7-11(8-6-10)25(19,23)24/h1-9H,(H2,19,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA1 by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this Ligand-Target Pair | |