null

SMILES: COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)OCC[Si](C)(C)C

InChI Key: InChIKey=KLSIUGBMIOWZCP-BKHJTQGXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse))	BDBM50262593 (2-((2S,3R,4S)-4-(2-naphthamido)-3-hydroxy-6-((2-me...) Show SMILES COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)OCC[Si](C)(C)C |r| Show InChI InChI=1S/C32H40N2O9Si/c1-40-13-14-41-20-43-24-11-12-26-25(18-24)29(33-31(38)23-10-9-21-7-5-6-8-22(21)17-23)30(37)27(19-28(35)36)34(26)32(39)42-15-16-44(2,3)4/h5-12,17-18,27,29-30,37H,13-16,19-20H2,1-4H3,(H,33,38)(H,35,36)/t27-,29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Binding affinity to mouse Mcl-1 expressed in Escherichia coli BL21 cells				Bioorg Med Chem 16: 7443-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.023 BindingDB Entry DOI: 10.7270/Q29023K1
					More data for this Ligand-Target Pair
Bcl2-associated agonist of cell death (Mus musculus (mouse))	BDBM50262593 (2-((2S,3R,4S)-4-(2-naphthamido)-3-hydroxy-6-((2-me...) Show SMILES COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)OCC[Si](C)(C)C |r| Show InChI InChI=1S/C32H40N2O9Si/c1-40-13-14-41-20-43-24-11-12-26-25(18-24)29(33-31(38)23-10-9-21-7-5-6-8-22(21)17-23)30(37)27(19-28(35)36)34(26)32(39)42-15-16-44(2,3)4/h5-12,17-18,27,29-30,37H,13-16,19-20H2,1-4H3,(H,33,38)(H,35,36)/t27-,29-,30-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cells				Bioorg Med Chem 16: 7443-9 (2008) Article DOI: 10.1016/j.bmc.2008.06.023 BindingDB Entry DOI: 10.7270/Q29023K1
					More data for this Ligand-Target Pair